Introduction：Basic information about CAS 60388-53-6|Amethopterin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Amethopterin |
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| CAS Number | 60388-53-6 | Molecular Weight | 454.43900 |
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| Density | 1.536 g/cm3 | Boiling Point | / |
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| Molecular Formula | C20H22N8O5 | Melting Point | 195ºC (dec.)(lit.) |
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| MSDS | / | Flash Point | / |
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Names
| Name | (+/-)amethopterin |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.536 g/cm3 |
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| Melting Point | 195ºC (dec.)(lit.) |
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| Molecular Formula | C20H22N8O5 |
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| Molecular Weight | 454.43900 |
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| Exact Mass | 454.17100 |
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| PSA | 210.54000 |
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| LogP | 1.82170 |
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| InChIKey | FBOZXECLQNJBKD-UHFFFAOYSA-N |
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| SMILES | CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- MA1224100
- CHEMICAL NAME :
- Glutamic acid, N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)b enzoyl)-, DL-
- CAS REGISTRY NUMBER :
- 60388-53-6
- LAST UPDATED :
- 199610
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C20-H22-N8-O5
- MOLECULAR WEIGHT :
- 454.50
- WISWESSER LINE NOTATION :
- T66 BN DN GN JNJ CZ EZ H1N1&R DVMYMQ2VQ -DL
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 32 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 29,43,1982
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Safety Information
| Hazard Codes | T |
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| Risk Phrases | R46;R61 |
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| Safety Phrases | S45-S53 |
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| RIDADR | UN 1544 6.1/PG 2 |
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Synonyms
| amethopterin |
| 4-amino-N10-methylpteroylglutamic acid |
| EINECS 262-213-7 |
| MFCD00150845 |
| 4-amino-10-methylpteroyl-glutamic acid |
| D-methionine-R-sulfoximine |
| D-Methotrexat |
| 2S,5S-Methionine sulfoximine |
