CAS 85-43-8|1,2,3,6-Tetrahydrophthalic anhydride

Introduction:Basic information about CAS 85-43-8|1,2,3,6-Tetrahydrophthalic anhydride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name1,2,3,6-Tetrahydrophthalic anhydride
CAS Number85-43-8Molecular Weight152.147
Density1.3±0.1 g/cm3Boiling Point305.6±42.0 °C at 760 mmHg
Molecular FormulaC8H8O3Melting Point101-102°C
MSDS/Flash Point148.3±25.1 °C

Names

NameCis-1,2,3,6-Tetrahydrophthalic Anhydride
SynonymMore Synonyms

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point305.6±42.0 °C at 760 mmHg
Melting Point101-102°C
Molecular FormulaC8H8O3
Molecular Weight152.147
Flash Point148.3±25.1 °C
Exact Mass152.047348
PSA43.37000
LogP0.10
Vapour Pressure0.0±0.6 mmHg at 25°C
Index of Refraction1.529
InChIKeyKMOUUZVZFBCRAM-UHFFFAOYSA-N
SMILESO=C1OC(=O)C2CC=CCC12

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GW5775000
CHEMICAL NAME :
4-Cyclohexene-1,2-dicarboxylic anhydride
CAS REGISTRY NUMBER :
85-43-8
BEILSTEIN REFERENCE NO. :
0082340
LAST UPDATED :
199710
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C8-H8-O3
MOLECULAR WEIGHT :
152.16
WISWESSER LINE NOTATION :
T56 BVOV GUTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,322,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,322,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>294 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 29(12),37,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 29(12),37,1985
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>294 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 29(12),37,1985
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,780,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 29(12),37,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
3500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 29(12),37,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2931 No. of Facilities: 39 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 1584 (estimated) No. of Female Employees: 547 (estimated)

Safety Information

Risk PhrasesR41
Safety PhrasesS26-S36/37/39
RIDADR2698
Packaging GroupIII
Hazard Class8

Synonyms

MFCD00005916
3a,4,7,7a-Tetrahydroisobenzofuran-1,3-dione
EINECS 201-605-4
Tetrahydrophthalic Anhydride
1,2,3,6-Tetrahydrophthalic anhydride
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