Introduction：Basic information about CAS 202821-81-6|BMS 191011, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | BMS 191011 |
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| CAS Number | 202821-81-6 | Molecular Weight | 370.71 |
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| Density | 1.516g/cm3 | Boiling Point | 443.965ºC at 760 mmHg |
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| Molecular Formula | C16H10ClF3N2O3 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 222.302ºC |
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| Symbol |
GHS06 | Signal Word | Danger |
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Names
| Name | 3-[(5-chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-one |
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| Synonym | More Synonyms |
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BMS 191011 BiologicalActivity
| Description | BMS-191011 (BMS-A) is an opener of the large-conductance, Ca2++-activated potassium (maxi-K) channel, effective in stroke models[1]. |
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| Related Catalog | Research Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium Channel |
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| References | [1]. Romine JL, et al. 3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3H)-one, BMS-191011: opener of large-conductance Ca(2+)-activated potassium (maxi-K) channels, identification, solubility, and SAR. J Med Chem. 2007 Feb 8;50(3):528-42. |
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Chemical & Physical Properties
| Density | 1.516g/cm3 |
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| Boiling Point | 443.965ºC at 760 mmHg |
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| Molecular Formula | C16H10ClF3N2O3 |
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| Molecular Weight | 370.71 |
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| Flash Point | 222.302ºC |
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| Exact Mass | 370.03300 |
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| PSA | 68.26000 |
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| LogP | 3.92940 |
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| Vapour Pressure | 0mmHg at 25°C |
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| Index of Refraction | 1.598 |
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| InChIKey | QKOWACXSXTXRKA-UHFFFAOYSA-N |
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| SMILES | O=c1oc(-c2ccc(C(F)(F)F)cc2)nn1Cc1cc(Cl)ccc1O |
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| Storage condition | 2-8℃ |
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Safety Information
| Symbol |
GHS06 |
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| Signal Word | Danger |
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| Hazard Statements | H301-H413 |
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| Precautionary Statements | P301 + P310 |
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| RIDADR | UN 2811 6.1 / PGIII |
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| HS Code | 2934999090 |
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Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Bms-a |
| HMS3269L09 |
| UNII-LW7MXS978N |
| 3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3H)-one |
