Introduction：Basic information about CAS 23243-68-7|3,6-Dioxaoctanedioic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3,6-Dioxaoctanedioic acid |
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| CAS Number | 23243-68-7 | Molecular Weight | 178.14000 |
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| Density | 1.375g/cm3 | Boiling Point | 429.2ºC at 760mmHg |
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| Molecular Formula | C6H10O6 | Melting Point | 68-71℃ |
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| MSDS | / | Flash Point | 182.6ºC |
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Names
| Name | 2-[2-(carboxymethoxy)ethoxy]acetic acid |
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| Synonym | More Synonyms |
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3,6-Dioxaoctanedioic acid BiologicalActivity
| Description | 36-Dioxaoctanedioic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.375g/cm3 |
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| Boiling Point | 429.2ºC at 760mmHg |
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| Melting Point | 68-71℃ |
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| Molecular Formula | C6H10O6 |
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| Molecular Weight | 178.14000 |
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| Flash Point | 182.6ºC |
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| Exact Mass | 178.04800 |
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| PSA | 93.06000 |
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| Vapour Pressure | 1.43E-08mmHg at 25°C |
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| Index of Refraction | 1.474 |
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| InChIKey | CQWXKASOCUAEOW-UHFFFAOYSA-N |
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| SMILES | O=C(O)COCCOCC(=O)O |
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| Storage condition | Store below +30°C. |
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Safety Information
| Hazard Codes | C: Corrosive; |
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| Risk Phrases | R34 |
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| Safety Phrases | 26-36/37/39-45-27-22 |
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| RIDADR | UN 3261 |
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| Packaging Group | III |
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| HS Code | 2918990090 |
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Customs
| HS Code | 2918990090 |
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| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| 2,2'-(ethane-1,2-diylbis(oxy))diacetic acid |
| 3,6-dioxaoctadioic acid |
| 3,6-dioxoctanedioic acid |
| 3,6-dioxa-1,8-octanedioic acid |
| 3,6-dioxaoctane-1,8-dioic acid |
| 3,6-DIOXAOCTANEDIOIC ACID |
| (2-carboxymethoxyethoxy)acetic acid |
| 3,6-dioxaoctandioic acid |
