CAS 73874-95-0|4-(N-BOC-AMINO)PIPERIDINE
| Common Name | 4-(N-BOC-AMINO)PIPERIDINE | ||
|---|---|---|---|
| CAS Number | 73874-95-0 | Molecular Weight | 200.28 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 304.8±31.0 °C at 760 mmHg |
| Molecular Formula | C10H20N2O2 | Melting Point | 162-166 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 138.2±24.8 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 4-Boc-aminopiperidine |
|---|---|
| Synonym | More Synonyms |
4-(N-BOC-AMINO)PIPERIDINE BiologicalActivity
| Description | 4-Boc-aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| In Vitro | 4-(N-Boc-amino)piperidine 是一种有机结构单元。它已被用于合成氨基哌啶抗病毒趋化因子 (CC motif) 受体 5 (CCR5) 拮抗剂和抗菌药物。 |
| References | [1]. Burrows, JN, Cumming, JG, Fillery, SM, et al. Modulators of the human CCR5 receptor. Part 1: Discovery and initial SAR of 1-(3,3-diphenylpropyl)-piperidinyl amides and ureas Bioorg. Med. Chem. Lett.15(1 )25-28(2005) [2]. Reck, F., Alm, R., Brassil, P., et al.Novel N-linked aminopiperidine inhibitors of bacterial topoisomerase type II: Broad-spectrum antibacterial agents with reduced hERG activityJ. Med . Chem.54(22)7834-7847(2011) |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 304.8±31.0 °C at 760 mmHg |
| Melting Point | 162-166 °C(lit.) |
| Molecular Formula | C10H20N2O2 |
| Molecular Weight | 200.28 |
| Flash Point | 138.2±24.8 °C |
| Exact Mass | 200.152481 |
| PSA | 50.36000 |
| LogP | 1.32 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.480 |
| InChIKey | CKXZPVPIDOJLLM-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)NC1CCNCC1 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933399090 |
Customs
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles3
More Articles| Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent Anti-HIV-1 activity. J. Med. Chem. 49 , 2784, (2006) We incorporated various polar groups into previously described piperidine-4-carboxamide CCR5 antagonists to improve their metabolic stability in human hepatic microsomes. Introducing a carbamoyl group... | |
| Synthesis of potent oxindole CDK2 inhibitors. Bioorg. Med. Chem. 11 , 1873-1881, (2003) A series of oxindole CDK2 inhibitors was synthesized. These novel analogues have a saturated monosubstituted cyclic moiety at their C-4 position that mimics the ribofuranoside of ATP. This substitutio... | |
| Poly (2-isopropyl-2-oxazoline)-poly (L-glutamate) block copolymers through ammonium-mediated NCA polymerization. Meyer M and Schlaad H. Macromolecules 39(11) , 3967-3970, (2006) |
Synonyms
| 2-Methyl-2-propanyl 4-amino-1-piperidinecarboxylate |
| Carbamic acid, N-4-piperidinyl-, 1,1-dimethylethyl ester |
| MFCD00798171 |
| methanol, 1-(1,1-dimethylethoxy)-1-(4-piperidinylimino)-, (E)- |
| tert-butyl N-piperidin-4-ylcarbamate |
| tert-butyl-piperidin-4-ylcarbamat |
| 2-Methyl-2-propanyl 4-piperidinylcarbamate |
| tert-butyl piperidin-4-ylcarbamate |
| 4-(N-BOC-AMINO)PIPERIDINE |
| 4-(tert-Butoxycarbonyl)-aminopiperidine |
| 4-N-BOC-Aminopiperidine |
| 4-N-(tert-Butoxycarbonyl)aminopiperidine |
